MIR4439 (microRNA 4439)

Gene Basic Information

Gene Basic Information

symbol:
MIR4439
locus group:
non-coding RNA
location:
2q36.2
gene_family:
MicroRNAs
alias symbol:
hsa-mir-4439
alias name:
None
entrez id:
100616207
ensembl gene id:
ENSG00000263828
ucsc gene id:
uc021vxm.1
refseq accession:
NR_039641
hgnc_id:
HGNC:41622
approved reserved:
2011-05-02

Chromosome Location

Chromosome Location

2q36.2

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR4439     Wikipedia entry for MIR4439

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR4439:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR4439:           Showing partial SNPs
rs281519       rs281520       rs281521       rs590233       rs648508       rs648887       rs683755       rs4673129       rs7340148       rs9288597       rs10933075       rs73083785       rs73083786       rs74621291       rs75071128       rs77582738       rs78267865      

Gene Expression

Gene Expression

Tissue expression of MIR4439:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GACTGATACCTTGGAGGCA
59
GATACCTTAGAGGCATTTGCT
58
CCAGTGACTGATACCTTGG
57
CTTAGAGGCATTTGCTTTGTG
58
CCAGTGACTGATACCTTGGA
59
CTTAGAGGCATTTGCTTTGTG
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR4439 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR4439:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR4439:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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