MIR4504 (microRNA 4504)

Gene Basic Information

Gene Basic Information

symbol:
MIR4504
locus group:
non-coding RNA
location:
14q21.3
gene_family:
MicroRNAs
alias symbol:
hsa-mir-4504
alias name:
None
entrez id:
100616261
ensembl gene id:
ENSG00000264712
ucsc gene id:
uc032bbn.2
refseq accession:
NR_039726
hgnc_id:
HGNC:41624
approved reserved:
2011-05-02

Chromosome Location

Chromosome Location

14q21.3

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR4504     Wikipedia entry for MIR4504

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR4504:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR4504:           Showing partial SNPs
rs4901011       rs61584633       rs73277317       rs73277322       rs74387776       rs111526615       rs112771654       rs112896498       rs113398347       rs113806201       rs113989112       rs116110419       rs117130120       rs139217975       rs139818330       rs141511886       rs143232054      

Gene Expression

Gene Expression

Tissue expression of MIR4504:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
TGTCCTCCAGGTTCATCTC
58
CATCTCTATTGTCACAAATGGTCC
59
AATGTCCTCCAGGTTCATCTC
59
TCTCTATTGTCACAAATGGTCC
58
CACCTAAGATAATGTCCTCCAG
57
CACAAATGGTCCATGCCAC
59

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR4504 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR4504:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR4504:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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