MIR466 (microRNA 466)
- symbol:
- MIR466
- locus group:
- non-coding RNA
- location:
- 3p23
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-466
- alias name:
- None
- entrez id:
- 100423038
- ensembl gene id:
- ENSG00000265376
- ucsc gene id:
- uc062htg.1
- refseq accession:
- NR_130459
- hgnc_id:
- HGNC:38359
- approved reserved:
- 2010-04-30
MicroRNAs (miRNAs) are short (20–24 nt) noncoding RNAs that post-transcriptionally regulate gene expression in multicellular organisms by affecting mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs), which can be either protein-coding or noncoding. The primary transcript is cleaved by Drosha ribonuclease III to yield an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which cytoplasmic Dicer further cleaves to produce the mature miRNA and antisense miRNA star (miRNA*) product. The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly leads to translational repression or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR466 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR466:
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