MIR4738 (microRNA 4738)

Gene Basic Information

Gene Basic Information

symbol:
MIR4738
locus group:
non-coding RNA
location:
17q25.1
gene_family:
MicroRNAs
alias symbol:
hsa-mir-4738
alias name:
None
entrez id:
100616282
ensembl gene id:
ENSG00000283853
ucsc gene id:
uc021udc.1
refseq accession:
NR_039892
hgnc_id:
HGNC:41679
approved reserved:
2011-05-02

Chromosome Location

Chromosome Location

17q25.1

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR4738     Wikipedia entry for MIR4738

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR4738:[NCBI]
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Gene Variants

Gene Variants

SNP variants of MIR4738:           Showing partial SNPs
rs2125345       rs7220730       rs9903538       rs11335367       rs11655389       rs55885223       rs63641660       rs73352133       rs75137507       rs75277629       rs114424860       rs117106577       rs138353752       rs140282972       rs140854686       rs144216044       rs144991801      

Gene Expression

Gene Expression

Tissue expression of MIR4738:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GTCGCATTTCTCCTTCTTACC
59
GTTTCATGGAAAGGCTTCCC
60
ATTTCTCCTTCTTACCAGCG
58
CTCCAGTTTCATGGAAAGGC
59
CATTTCTCCTTCTTACCAGCG
59
TCCAGTTTCATGGAAAGGC
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR4738 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR4738:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR4738:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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