MIR4762 (microRNA 4762)

Gene Basic Information

Gene Basic Information

symbol:
MIR4762
locus group:
non-coding RNA
location:
22q13.31
gene_family:
MicroRNAs
alias symbol:
hsa-mir-4762
alias name:
None
entrez id:
100616253
ensembl gene id:
ENSG00000264160
ucsc gene id:
uc021wrl.1
refseq accession:
NR_039919
hgnc_id:
HGNC:41603
approved reserved:
2011-05-02

Chromosome Location

Chromosome Location

22q13.31

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR4762     Wikipedia entry for MIR4762

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR4762:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR4762:           Showing partial SNPs
rs2239398       rs4823322       rs5765607       rs6007156       rs9614515       rs9614774       rs11912739       rs41524547       rs56898998       rs58099513       rs59406530       rs60308683       rs60514881       rs73444641       rs80056359       rs111656853       rs111989297      

Gene Expression

Gene Expression

Tissue expression of MIR4762:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
CCCAAATCTTGATCAGAAGCC
59
ACCACAAATCTTGATCAGAAGC
59
CCAAATCTTGATCAGAAGCCT
58
ACCACAAATCTTGATCAGAAGC
59
CCCAAATCTTGATCAGAAGCC
59
CCACAAATCTTGATCAGAAGC
57

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR4762 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR4762:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR4762:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

Vitreous transcriptomic profiling reveals miR-4762 as a potential diagnostic biomarker and modulator of disease pathophysiology in Tubercular Uveitis.
Kakkar K, Kaur M, Gupta V, Bansal R, Dogra M, Kumar R, Kar SS, Kaur P, Sharma S, Patra S, Maitra A, Kalyan M, Verma I Tuberculosis (Edinb) IF: 2.9 2026-05-00

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