MIR525 (microRNA 525)

Gene Basic Information

Gene Basic Information

symbol:
MIR525
locus group:
non-coding RNA
location:
19q13.42
gene_family:
MicroRNAs
alias symbol:
hsa-mir-525
alias name:
None
entrez id:
574470
ensembl gene id:
ENSG00000207711
ucsc gene id:
uc021uzv.1
refseq accession:
NR_030192
hgnc_id:
HGNC:32102
approved reserved:
2005-07-15

Chromosome Location

Chromosome Location

19q13.42

Gene Summary

Gene Summary

ChineseEnglish

MicroRNAs (miRNAs) are short (20–24 nt) noncoding RNAs that participate in post-transcriptional regulation of gene expression in multicellular organisms by affecting mRNA stability and translation. They are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. Pri-miRNAs are cleaved by the RNase III enzyme Drosha to produce ~70-nt stem-loop precursor miRNAs (pre-miRNAs), which are further processed by cytoplasmic Dicer to generate mature miRNA and antisense miRNA star (miRNA*) products. Mature miRNAs are incorporated into the RNA-induced silencing complex (RISC), where imperfect base pairing with target mRNAs most often leads to translational repression or destabilization. The RefSeq record represents a predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]

OMIM entry for MIR525     Wikipedia entry for MIR525

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR525:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR525:           Showing partial SNPs
rs10417538       rs139075157       rs142380555       rs192377320       rs555856544       rs570194101       rs8100449       rs11883365       rs73057650       rs111678424       rs143660166       rs143899016       rs187060724       rs191832879       rs532998996       rs551457346       rs569774022      

Gene Expression

Gene Expression

Tissue expression of MIR525:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GGGATGCACTTTCTCTTATGTG
59
CAAACCGTAACGCTCTAAAGG
59
CAGAGGGATGCACTTTCTC
57
CCGTAACGCTCTAAAGGGA
59
GGGATGCACTTTCTCTTATGTG
59
AAACCGTAACGCTCTAAAGG
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR525 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR525:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR525:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Hypertensive disease 0.000542884 2 0 BeFree
Malignant neoplasm of liver 0.000271442 1 0 BeFree
Pregnancy Complications 0.000271442 1 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.000271442 1 0 BeFree

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