MIR548H1 (microRNA 548h-1)

Gene Basic Information

Gene Basic Information

symbol:
MIR548H1
locus group:
non-coding RNA
location:
14q23.2
gene_family:
MicroRNAs
alias symbol:
hsa-mir-548h-1
alias name:
None
entrez id:
100313830
ensembl gene id:
ENSG00000221537
ucsc gene id:
uc032beg.1
refseq accession:
NR_031677
hgnc_id:
HGNC:35342
approved reserved:
2008-11-03

Chromosome Location

Chromosome Location

14q23.2

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR548H1     Wikipedia entry for MIR548H1

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR548H1:[NCBI]
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Gene Variants

Gene Variants

SNP variants of MIR548H1:           Showing partial SNPs
rs8016809       rs8018154       rs8022428       rs10136633       rs17101651       rs28493185       rs56123497       rs57319207       rs58812298       rs76350902       rs76656506       rs79674350       rs80217642       rs114381097       rs115703723       rs116339884       rs117011000      

Gene Expression

Gene Expression

Tissue expression of MIR548H1:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
TCTGTCCATTAGGTGGGTG
58
CTGGCTTAATATTAGGTCAGTGC
59
TCTGTCCATTAGGTGGGTG
58
TGGCTTAATATTAGGTCAGTGC
58
TCTGTCCATTAGGTGGGTG
58
GGCTTAATATTAGGTCAGTGCA
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR548H1 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR548H1:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR548H1:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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