MIR548I1 (microRNA 548i-1)

Gene Basic Information

Gene Basic Information

symbol:
MIR548I1
locus group:
non-coding RNA
location:
3q21.2
gene_family:
MicroRNAs
alias symbol:
hsa-mir-548i-1
alias name:
None
entrez id:
100302204
ensembl gene id:
ENSG00000221737
ucsc gene id:
uc021xdg.1
refseq accession:
NR_031687
hgnc_id:
HGNC:35352
approved reserved:
2008-11-03

Chromosome Location

Chromosome Location

3q21.2

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR548I1     Wikipedia entry for MIR548I1

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR548I1:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR548I1:           Showing partial SNPs
rs9863382       rs35313026       rs35550688       rs62270518       rs72493110       rs72493111       rs72493112       rs74511939       rs74770527       rs74991723       rs75250182       rs76444712       rs77379384       rs77466845       rs77663620       rs77859147       rs78498048      

Gene Expression

Gene Expression

Tissue expression of MIR548I1:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
CACCCTATTAGGTTGGTGC
58
GGACAAAGTTTGGTAGAAGGA
58
ACCCTATTAGGTTGGTGCA
58
GGACAAAGTTTGGTAGAAGGAG
59
ACCCTATTAGGTTGGTGCA
58
GGACAAAGTTTGGTAGAAGGA
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR548I1 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR548I1:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR548I1:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

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