MIR550B1 (microRNA 550b-1)
- symbol:
- MIR550B1
- locus group:
- non-coding RNA
- location:
- 7p14.3
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-550b-1
- alias name:
- None
- entrez id:
- 100500883
- ensembl gene id:
- ENSG00000283237
- ucsc gene id:
- None
- refseq accession:
- NR_037513
- hgnc_id:
- HGNC:38992
- approved reserved:
- 2010-09-15
MIR550B1 is a microRNA (miRNA), a short (20–24 nucleotide) noncoding RNA that participates in post-transcriptional regulation of gene expression in multicellular organisms by affecting mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. The primary transcript is cleaved by Drosha ribonuclease III to produce an approximately 70-nucleotide stem-loop precursor miRNA (pre-miRNA), which is further cleaved by cytoplasmic Dicer to yield mature miRNA and antisense star miRNA (miRNA*). The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly leads to translational repression or destabilization of the target mRNA. RefSeq represents the predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR550B1 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR550B1:
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