MIR6128 (microRNA 6128)
- symbol:
- MIR6128
- locus group:
- non-coding RNA
- location:
- 11q12.1
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-6128
- alias name:
- None
- entrez id:
- 102465135
- ensembl gene id:
- ENSG00000274770
- ucsc gene id:
- None
- refseq accession:
- NR_106743
- hgnc_id:
- HGNC:50109
- approved reserved:
- 2014-03-24
MicroRNAs (miRNAs) are short (20–24 nucleotide) noncoding RNAs that participate in post-transcriptional regulation of gene expression in multicellular organisms by affecting mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as parts of capped and polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. The primary transcript is cleaved by the RNase III enzyme Drosha to produce an approximately 70-nucleotide stem-loop precursor miRNA (pre-miRNA), which is further cleaved by cytoplasmic Dicer to yield mature miRNA and antisense miRNA star (miRNA*) products. Mature miRNA is incorporated into an RNA-induced silencing complex (RISC), where it recognizes target mRNAs through imperfect base pairing and most commonly causes translational inhibition or destabilization of the target mRNA. RefSeq represents the predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR6128 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR6128:
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