MIR6134 (microRNA 6134)
- symbol:
- MIR6134
- locus group:
- non-coding RNA
- location:
- Xp21.3
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-6134
- alias name:
- None
- entrez id:
- 102465140
- ensembl gene id:
- ENSG00000277569
- ucsc gene id:
- None
- refseq accession:
- NR_106750
- hgnc_id:
- HGNC:49951
- approved reserved:
- 2014-03-24
MicroRNAs (miRNAs) are short (20–24 nt) noncoding RNAs that regulate gene expression post-transcriptionally in multicellular organisms by affecting mRNA stability and translation. They are transcribed by RNA polymerase II as parts of capped, polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. Pri-miRNAs are cleaved by the RNase III enzyme Drosha to produce approximately 70-nt stem-loop precursor miRNAs (pre-miRNAs), which are further processed by cytoplasmic Dicer into mature miRNA and antisense miRNA* products. The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing and most often leads to translational repression or destabilization of the target mRNA. This RefSeq representative predicts a microRNA stem-loop.
Gene Ontology
Subcellular localization of MIR6134 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR6134:
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