MIR630 (microRNA 630)

Gene Basic Information

Gene Basic Information

symbol:
MIR630
locus group:
non-coding RNA
location:
15q24.1
gene_family:
MicroRNAs
alias symbol:
hsa-mir-630
alias name:
None
entrez id:
693215
ensembl gene id:
ENSG00000283798
ucsc gene id:
uc021spw.1
refseq accession:
NR_030359
hgnc_id:
HGNC:32886
approved reserved:
2006-05-17

Chromosome Location

Chromosome Location

15q24.1

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR630     Wikipedia entry for MIR630

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR630:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR630:           Showing partial SNPs
rs11629713       rs16957161       rs17825866       rs28649484       rs112478355       rs115691230       rs140047055       rs141006963       rs141628879       rs144475179       rs144852504       rs145222485       rs147936206       rs149150695       rs150011709       rs150703476       rs183280849      

Gene Expression

Gene Expression

Tissue expression of MIR630:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR630 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR630:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR630:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Tumor Progression 0.000814326 3 0 BeFree
Malignant neoplasm of stomach 0.000542884 2 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Colorectal Cancer 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Malignant neoplasm of kidney 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Conventional (Clear Cell) Renal Cell Carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree

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