MIR642B (microRNA 642b)
- symbol:
- MIR642B
- locus group:
- non-coding RNA
- location:
- 19q13.32
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-642b
- alias name:
- None
- entrez id:
- 100500845
- ensembl gene id:
- ENSG00000283212
- ucsc gene id:
- None
- refseq accession:
- NR_037512
- hgnc_id:
- HGNC:38902
- approved reserved:
- 2010-09-15
MicroRNAs (miRNAs) are short (20–24 nt) noncoding RNAs that post-transcriptionally regulate gene expression in multicellular organisms by affecting mRNA stability and translation. They are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. Pri-miRNAs are cleaved by Drosha ribonuclease III to generate ~70-nt stem-loop precursor miRNAs (pre-miRNAs), which are further processed by cytoplasmic Dicer into mature miRNAs and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing and most often leads to translational inhibition or destabilization of the target mRNA. This RefSeq entry represents a predicted microRNA stem-loop for MIR642B. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR642B (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR642B:
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