MIR647 (microRNA 647)

Gene Basic Information

Gene Basic Information

symbol:
MIR647
locus group:
non-coding RNA
location:
20q13.33
gene_family:
MicroRNAs
alias symbol:
hsa-mir-647
alias name:
None
entrez id:
693232
ensembl gene id:
ENSG00000207554
ucsc gene id:
uc021wgn.1
refseq accession:
NR_030377
hgnc_id:
HGNC:32903
approved reserved:
2006-05-17

Chromosome Location

Chromosome Location

20q13.33

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR647     Wikipedia entry for MIR647

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR647:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR647:           Showing partial SNPs
rs2427569       rs2427571       rs73147065       rs77043678       rs111545918       rs111873930       rs112538127       rs112709026       rs113363637       rs115508557       rs117512405       rs141070251       rs145670009       rs148141381       rs183155560       rs188637168       rs191451021      

Gene Expression

Gene Expression

Tissue expression of MIR647:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR647 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR647:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR647:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

Related Publications

Related Publications

Comprehensive transcriptomics and proteomics analysis of neointima formation in human saphenous vein: implications for bypass graft disease.
Kim DS, Goo B, Shi H, Dong S, Weintraub DS, Coffey P, Veerapaneni P, Chouhaita R, Guduru M, Cyriac N, Aboud G, Ong V, Cave S, Greenway J, Mundkur R, Ahmadieh S, Harb R, Ogbi M, Fulton DJ, Huo Y, Zhang W, Long X, Guha A, Kim HW, Shi Y, Rice RD, Zhou J, Chiang AWT, Gallo DR, Patel VS, Lee R, Weintraub NL Am J Physiol Heart Circ Physiol IF: 3.9 2026-02-01

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