MIR6777 (microRNA 6777)
- symbol:
- MIR6777
- locus group:
- non-coding RNA
- location:
- 17p11.2
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-6777
- alias name:
- None
- entrez id:
- 102465466
- ensembl gene id:
- ENSG00000274111
- ucsc gene id:
- None
- refseq accession:
- NR_106835
- hgnc_id:
- HGNC:50173
- approved reserved:
- 2014-03-24
MicroRNAs (miRNAs) are short (20–24 nucleotide) noncoding RNAs that participate in post-transcriptional regulation of gene expression in multicellular organisms by affecting mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. The primary transcript is cleaved by Drosha ribonuclease III to produce an approximately 70-nucleotide stem-loop precursor miRNA (pre-miRNA), which is further cleaved by cytoplasmic Dicer ribonuclease to yield mature miRNA and antisense star miRNA (miRNA*) products. Mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing and most commonly results in translational repression or destabilization of the target mRNA. The RefSeq represents a predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR6777 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR6777:
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