MIR6890 (microRNA 6890)

symbol:
MIR6890
locus group:
non-coding RNA
location:
3p21.31
gene_family:
MicroRNAs
alias symbol:
hsa-mir-6890
alias name:
None
entrez id:
102465536
ensembl gene id:
ENSG00000284488
ucsc gene id:
None
refseq accession:
NR_106950
hgnc_id:
HGNC:49990
approved reserved:
2014-03-24
3p21.31
ChineseEnglish

MIR6890 is a microRNA (miRNA), a short 20–24 nucleotide noncoding RNA that helps regulate gene expression post-transcriptionally in multicellular organisms by affecting mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as parts of capped and polyadenylated primary transcripts (pri-miRNAs), which can be protein-coding or noncoding. The primary transcript is cleaved by the nuclear RNase III enzyme Drosha to produce an approximately 70-nucleotide stem-loop pre-miRNA, which cytoplasmic Dicer further cleaves to yield the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing and most commonly causes translational inhibition or destabilization of the target mRNA. RefSeq represents this predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]

Nucleotide sequence of MIR6890:[NCBI]
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SNP variants of MIR6890:           Showing partial SNPs
rs4521268       rs11539148       rs60002662       rs111912618       rs116187955       rs116738354       rs138204612       rs138456917       rs138685078       rs141072684       rs142316938       rs142517070       rs142711777       rs143072084       rs143462532       rs143724892       rs144092780      

Tissue expression of MIR6890:    [UniProt]

Gene expression across tissues
Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
      No data available

Subcellular localization of MIR6890 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR6890:

microRNAs potentially regulating MIR6890:     

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Interacting Gene Interaction Source/Score
Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

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