MIR7-1 (microRNA 7-1)

Gene Basic Information

Gene Basic Information

symbol:
MIR7-1
locus group:
non-coding RNA
location:
9q21.32
gene_family:
MicroRNAs
alias symbol:
hsa-mir-7-1
alias name:
None
entrez id:
407043
ensembl gene id:
ENSG00000284179
ucsc gene id:
uc004ano.1
refseq accession:
NR_029605
hgnc_id:
HGNC:31638
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

9q21.32

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR7-1     Wikipedia entry for MIR7-1

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR7-1:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR7-1:           Showing partial SNPs
rs296885       rs3214659       rs3214660       rs3750407       rs11140312       rs11140313       rs45547733       rs61755088       rs77120505       rs77476256       rs78280596       rs111450543       rs112635088       rs114279043       rs115346013       rs115527397       rs117595279      

Gene Expression

Gene Expression

Tissue expression of MIR7-1:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
ATGTTGGCCTAGTTCTGTG
57
CAGACTGTGATTTGTTGTCGA
59
ATGTTGGCCTAGTTCTGTG
57
CAGACTGTGATTTGTTGTCG
57
ATGTTGGCCTAGTTCTGTG
57
AGACTGTGATTTGTTGTCGA
57

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR7-1 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR7-1:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR7-1:     

Gene Interactions

Gene Interactions

BioGrid
Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Glioblastoma 0.00272435 1 0 LHGDN
Stomach Neoplasms 0.000271442 1 0 BeFree
Gastritis 0.000271442 1 0 BeFree
Neuroblastoma 0.000271442 1 0 BeFree

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