MIR7-2 (microRNA 7-2)

Gene Basic Information

Gene Basic Information

symbol:
MIR7-2
locus group:
non-coding RNA
location:
15q26.1
gene_family:
MicroRNAs
alias symbol:
hsa-mir-7-2
alias name:
None
entrez id:
407044
ensembl gene id:
ENSG00000207703
ucsc gene id:
uc010upm.2
refseq accession:
NR_029606
hgnc_id:
HGNC:31639
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

15q26.1

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR7-2     Wikipedia entry for MIR7-2

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR7-2:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR7-2:           Showing partial SNPs
rs1440127       rs1470108       rs1470109       rs6496506       rs7170666       rs12908122       rs12912117       rs28667006       rs34211216       rs35444926       rs41276928       rs41276930       rs74028186       rs74498786       rs74680244       rs76923654       rs77061174      

Gene Expression

Gene Expression

Tissue expression of MIR7-2:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
CTGGATACAGAGTGGACCG
59
CACCATTAGGTAGACTGGGA
58
CTGGATACAGAGTGGACCG
59
GTTGTTGAGCGCAGTAAGAC
60
CTGGATACAGAGTGGACCG
59
TTGTTGAGCGCAGTAAGAC
59

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR7-2 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR7-2:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR7-2:     

Gene Interactions

Gene Interactions

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Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

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