MIR8054 (microRNA 8054)

symbol:
MIR8054
locus group:
non-coding RNA
location:
11p14.3
gene_family:
MicroRNAs
alias symbol:
hsa-mir-8054
alias name:
None
entrez id:
102465860
ensembl gene id:
ENSG00000275868
ucsc gene id:
None
refseq accession:
NR_107021
hgnc_id:
HGNC:50177
approved reserved:
2014-03-24
11p14.3
ChineseEnglish

MIR8054 is represented in RefSeq as a predicted microRNA stem-loop. MicroRNAs (miRNAs) are short (20–24 nt) noncoding RNAs that post-transcriptionally regulate gene expression in multicellular organisms by affecting mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts (pri-miRNAs), which may be protein-coding or noncoding. Pri-miRNAs are cleaved by the RNase III enzyme Drosha to produce ~70-nt stem-loop precursor miRNAs (pre-miRNAs), which are further cleaved by cytoplasmic Dicer to generate mature miRNA and antisense miRNA* products. The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly leads to translational repression or destabilization of the target mRNA. [Provided by RefSeq, Sep 2009]

Nucleotide sequence of MIR8054:[NCBI]
Loading Gene Browser...
SNP variants of MIR8054:           Showing partial SNPs
rs1462557       rs7105063       rs7105389       rs10734332       rs10741968       rs11027206       rs34495913       rs34895821       rs61889945       rs61889946       rs74879592       rs75764590       rs76821472       rs77220851       rs77690975       rs77903397       rs79634645      

Tissue expression of MIR8054:    [UniProt]

Gene expression across tissues
Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GAAAGTACAGATCGGATGGGT
59
TACAATGGGAAGGCTTGCT
59
GAAAGTACAGATCGGATGGG
57
TACAATGGGAAGGCTTGCT
59
CGGATGGGTTCAATAGATTGC
59
CAATGAGATATGTACAATGGGAAGG
59
      No data available

Subcellular localization of MIR8054 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR8054:

microRNAs potentially regulating MIR8054:     

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Interacting Gene Interaction Source/Score
Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source

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