MIR8072 (microRNA 8072)
- symbol:
- MIR8072
- locus group:
- non-coding RNA
- location:
- 12q24.31
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-8072
- alias name:
- None
- entrez id:
- 102466877
- ensembl gene id:
- ENSG00000284425
- ucsc gene id:
- None
- refseq accession:
- NR_107039
- hgnc_id:
- HGNC:50174
- approved reserved:
- 2014-03-24
MicroRNAs (miRNAs) are short (20–24 nucleotide) noncoding RNAs that post-transcriptionally regulate gene expression in multicellular organisms by affecting both mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as parts of capped and polyadenylated primary transcripts (pri-miRNAs), which can be either protein-coding or noncoding. The primary transcript is cleaved by Drosha RNase III to produce an approximately 70-nucleotide stem-loop precursor miRNA (pre-miRNA), which is further cleaved by cytoplasmic Dicer to generate a mature miRNA and an antisense miRNA star (miRNA*) product. The mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly leads to translational repression or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR8072 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR8072:
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