MIR8080 (microRNA 8080)
- symbol:
- MIR8080
- locus group:
- non-coding RNA
- location:
- 2p12
- gene_family:
- MicroRNAs
- alias symbol:
- hsa-mir-8080
- alias name:
- None
- entrez id:
- 102465877
- ensembl gene id:
- ENSG00000276917
- ucsc gene id:
- None
- refseq accession:
- NR_107047
- hgnc_id:
- HGNC:49989
- approved reserved:
- 2014-03-24
MicroRNAs (miRNAs) are short (20–24 nt) noncoding RNAs that participate in post-transcriptional regulation of gene expression in multicellular organisms by affecting mRNA stability and translation. miRNAs are transcribed by RNA polymerase II as capped and polyadenylated primary transcripts (pri-miRNAs), which can be either protein-coding or noncoding. The primary transcript is cleaved by the RNase III enzyme Drosha to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by cytoplasmic Dicer to yield mature miRNA and antisense miRNA star (miRNA*) products. Mature miRNA is incorporated into the RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly leads to translational inhibition or destabilization of the target mRNA. The RefSeq represents a predicted microRNA stem-loop. [Provided by RefSeq, Sep 2009]
Gene Ontology
Subcellular localization of MIR8080 (and its protein):
- plasma membrane
- cytoplasm
- extracellular
- golgi
- vesicle
- cytoskeleton
- endoplasmic reticulum
- nucleus
- endosome
- lysosome
- mitochondrion
Gene Ontology (GO) terms for MIR8080:
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