MIR93 (microRNA 93)

Gene Basic Information

Gene Basic Information

symbol:
MIR93
locus group:
non-coding RNA
location:
7q22.1
gene_family:
MicroRNAs
alias symbol:
hsa-mir-93
alias name:
None
entrez id:
407050
ensembl gene id:
ENSG00000207757
ucsc gene id:
uc003usz.1
refseq accession:
NR_029510
hgnc_id:
HGNC:31645
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

7q22.1

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIR93     Wikipedia entry for MIR93

Gene Sequence

Gene Sequence

Nucleotide sequence of MIR93:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIR93:           Showing partial SNPs
rs12267       rs1527423       rs1569056       rs2261360       rs2261363       rs2307349       rs2307351       rs2307353       rs4729576       rs7799115       rs17447273       rs28665367       rs41274221       rs72631824       rs72631827       rs76705400       rs77603567      

Gene Expression

Gene Expression

Tissue expression of MIR93:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIR93 (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIR93:

Related microRNA

Related microRNA

microRNAs potentially regulating MIR93:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Osteosarcoma 0.120271442 2 0 BeFree_CTD_human
Colorectal Neoplasms 0.12 1 0 CTD_human
Malignant neoplasm of ovary 0.002638474 2 0 BeFree_GAD
Neoplasm Metastasis 0.002442977 9 0 BeFree
Carcinogenesis 0.002171535 8 0 BeFree
Breast Carcinoma 0.001357209 5 0 BeFree
Malignant neoplasm of breast 0.001357209 5 0 BeFree
Malignant neoplasm of stomach 0.001085767 4 0 BeFree
Stomach Carcinoma 0.001085767 4 0 BeFree
Malignant tumor of colon 0.001085767 4 0 BeFree

Related Publications

Related Publications

MiR-93-5p Loaded Lipid Nanoparticles Break the Dry Eye Vicious Cycle via Targeting MAP3K8.
Xu B, Ji X, Li L, Zhu L, Wang L, Kang J, Yang S, Fan T ACS Appl Mater Interfaces IF: 7.8 2026-04-08
[Correlation between Plasma microRNA Expression and Acute Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation].
Hu Bin, Fu Wei, Huang Si-Yong, Gao Xiao-Tong, Li Dan-Hui, Yan Xue-Qian, Zhang Yang-Ping, Liu Qiang, Liu Li, Liang Ying-Min Zhongguo Shi Yan Xue Ye Xue Za Zhi 2016-09-15
MIR106B and MIR93 prevent removal of bacteria from epithelial cells by disrupting ATG16L1-mediated autophagy.
Lu Changming, Chen Jianfeng, Xu Hua-Guo, Zhou Xianzheng, He Qiongqiong, Li Yu-Lin, Jiang Guoqing, Shan Yuxi, Xue Boxin, Zhao Rui-Xun, Wang Yong, Werle Kaitlin D, Cui Rutao, Liang Jiyong, Xu Zhi-Xiang Gastroenterology IF: 29.7 2014-02-18
MicroRNAs: new candidates for the regulation of the human cumulus-oocyte complex.
Assou S, Al-edani T, Haouzi D, Philippe N, Lecellier C-H, Piquemal D, Commes T, Aït-Ahmed O, Dechaud H, Hamamah S Hum Reprod IF: 6.8 2014-06-16
Genetic association of gastric cancer with miRNA clusters including the cancer-related genes MIR29, MIR25, MIR93 and MIR106: results from the EPIC-EURGAST study.
Espinosa-Parrilla Yolanda, Muñoz Xavier, Bonet Catalina, Garcia Nadia, Venceslá Adoración, Yiannakouris Nikos, Naccarati Alessio, Sieri Sabina, Panico Salvatore, Huerta José M, Barricarte Aurelio, Menéndez Virginia, Sánchez-Cantalejo Emilio, Dorronsoro Miren, Brennan Paul, Duarte-Salles Talita, B As Bueno-de-Mesquita H, Weiderpass Elisabete, Lund Eiliv, Clavel-Chapelon Françoise, Boutron-Ruault Marie-Christine, Racine Antoine, Numans Mattijs E, Tumino Rosario, Canzian Federico, Campa Daniele, Sund Malin, Johansson Mattias, Ohlsson Bodil, Lindkvist Björn, Overvad Kim, Tjønneland Anne, Palli Domenico, Travis Ruth C, Khaw Kay-Tee, Wareham Nick, Boeing Heiner, Nesi Gabriella, Riboli Elio, Gonzalez Carlos A, Sala Núria Int J Cancer IF: 4.9 2014-10-21
Expression of MiR200a, miR93, metastasis-related gene RECK and MMP2/MMP9 in human cervical carcinoma--relationship with prognosis.
Wang Ling, Wang Qiang, Li He-Lian, Han Li-Ying Asian Pac J Cancer Prev IF: 0.000 2014-01-07
Microarray profiling of monocytic differentiation reveals miRNA-mRNA intrinsic correlation.
Wang Jing, Xiang Guangxing, Mitchelson Keith, Zhou Yuxiang J Cell Biochem IF: 3.0 2011-12-07
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression.
Otsuka Motoyuki, Jing Qing, Georgel Philippe, New Liguo, Chen Jianming, Mols Johann, Kang Young Jun, Jiang Zhengfan, Du Xin, Cook Ryan, Das Subash C, Pattnaik Asit K, Beutler Bruce, Han Jiahuai Immunity IF: 30.6 2007-08-28
miRNA-93-5p and other miRNAs as predictors of coronary artery disease and STEMI.
O Sullivan John F, Neylon Antoinette, McGorrian Catherine, Blake Gavin J Int J Cardiol IF: 3.3 0000-00-00

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