MIRLET7G (microRNA let-7g)

Gene Basic Information

Gene Basic Information

symbol:
MIRLET7G
locus group:
non-coding RNA
location:
3p21.2
gene_family:
MicroRNAs
alias symbol:
hsa-let-7g
alias name:
None
entrez id:
406890
ensembl gene id:
ENSG00000199150
ucsc gene id:
uc011bee.3
refseq accession:
NR_029660
hgnc_id:
HGNC:31485
approved reserved:
2004-04-23

Chromosome Location

Chromosome Location

3p21.2

Gene Summary

Gene Summary

ChineseEnglish

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

OMIM entry for MIRLET7G     Wikipedia entry for MIRLET7G

Gene Sequence

Gene Sequence

Nucleotide sequence of MIRLET7G:[NCBI]
Loading Gene Browser...

Gene Variants

Gene Variants

SNP variants of MIRLET7G:           Showing partial SNPs
rs7643913       rs9631505       rs11714358       rs12171285       rs57179725       rs76033947       rs77278121       rs77340141       rs138557188       rs141646777       rs145909524       rs147974620       rs148900478       rs180924356       rs181279715       rs183668492       rs185847248      

Gene Expression

Gene Expression

Tissue expression of MIRLET7G:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
AGTTTGTACAGTTTGAGGGT
57
GTGGCCTGTACAGTTATCTC
58
GGTAGTAGTTTGTACAGTTTGAGG
59
TGTACAGTTATCTCCTGTACCG
59
GTAGTAGTTTGTACAGTTTGAGGG
59
CTGTACAGTTATCTCCTGTACC
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of MIRLET7G (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for MIRLET7G:

Related microRNA

Related microRNA

microRNAs potentially regulating MIRLET7G:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Liver carcinoma 0.000542884 2 0 BeFree
Diffuse Large B-Cell Lymphoma 0.000271442 1 0 BeFree
Rectal Carcinoma 0.000271442 1 0 BeFree

Related Publications

Related Publications

No related publications

Related Services

Related Services

Comments

Comments

Loading comments...

Log in to post comments Log In Sign Up

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2