PRY (PTPN13 like Y-linked)

Gene Basic Information

Gene Basic Information

symbol:
PRY
locus group:
protein-coding gene
location:
Yq11.223
gene_family:
alias symbol:
PTPN13LY|PRY1
alias name:
None
entrez id:
9081
ensembl gene id:
ENSG00000169789
ucsc gene id:
uc004fvh.1
refseq accession:
NM_004676
hgnc_id:
HGNC:14024
approved reserved:
2001-09-21

Chromosome Location

Chromosome Location

Yq11.223

Gene Summary

Gene Summary

ChineseEnglish

This gene is located in the non-recombining region of the Y chromosome and is specifically expressed in the testis. It encodes a protein with low similarity to protein tyrosine phosphatases, non-receptor type, and exists as two nearly identical copies within a palindromic region. This record represents the more telomeric copy. [Provided by RefSeq, Jul 2008]

OMIM entry for PRY     Wikipedia entry for PRY

Gene Sequence

Gene Sequence

Nucleotide sequence of PRY:[NCBI]
Loading Gene Browser...

Encoded Protein

Encoded Protein

Protein Sequence
1MGATGLGFLL SWRQDNLNGT DCQGCNILYF SETTGSMCSE
41LSLNRGLEAR RKKDLKDSFL WRYGKVGCIS LPLREMTAWI
81 NPPQISEIF QGYHQRVHGA DALSLQTNSL RSRLSSQCLG
121QSFLLRTLER GRGFRALGDI CGHVHEED
结构预测来自 AlphaFold DB（UniProt: O14603），颜色表示 pLDDT 置信度（深蓝高、黄橙低）。

Gene Variants

Gene Variants

SNP variants of PRY:           Showing partial SNPs
rs31183       rs31182       rs31181       rs31169      

Gene Expression

Gene Expression

Tissue expression of PRY:    [UniProt]

Gene expression across tissues

Gene Primers

Gene Primers

Forward Primer
Forward Tm
Reverse Primer
Reverse Tm
Score
GAACTTTCCTTGAACAGAGGT
58
AACCTTCCCATATCTCCAGAG
59
TGGCTTTCTACTTTCCTGGA
59
TATTGCATCCCTGGCAGTC
60
TGGCTTTCTACTTTCCTGGAG
60
TATTGCATCCCTGGCAGTC
60
ACTTTCCTTGAACAGAGGTC
58
CCAACCTTCCCATATCTCC
57
GGCTTTCTACTTTCCTGGAG
58
TATTGCATCCCTGGCAGTC
60
AACTTTCCTTGAACAGAGGTC
58
CAACCTTCCCATATCTCCAG
58

Transcription Factors

Transcription Factors

      No data available

Gene Ontology

Subcellular localization of PRY (and its protein):

[UniProt]     [GenomeNet]

" d="M482.414,245.296c3.539,4.293,4.455,10.009,0.202,11 c-4.244,0.996-4.983-10.983-8.293-8.438c-5.271,4.08,9.834,12.271,5.144,17.287c-3.717,3.607-6.172-5.75-10.839-1.976 c-4.673,3.776,6.781,7.299,2.831,11.326c-4.354,4.045-6.979-1.449-9.837-5.517c-1.193-1.742-2.059-3.851-3.595-2.748 c-1.516,1.078-1.854,1.795-0.938,3.666c2.374,4.854,9.235,10.119,5.156,12.535c-5.636,3.346-5.044-8.871-9.426-7.574 c-4.388,1.291,2.557,10.66-1.245,11.141c-4.089,0.545-3.483-10.239-6.979-8.575c-2.522,1.206-0.929,3.071-0.938,4.899 c0.004,1.32-0.964,3.6-2.372,4.062c-3.593,1.171-8.544-1.065-10.251-3.59c-6.04-8.93,0.396-15.997,4.639-7.015 c3.023,4.642,5.182,0.834,2.839-2.219c-1.032-1.354-4.309-5.901-0.781-7.252c2.904-1.113,4.271,1.941,5.985,4.592 c2.61,4.016,5.485,0.117,3.031-3.414c-1.828-2.633-2.74-3.803,3.156-7.42c6.405-4.369,6.52,3.869,10.077,0.646 c2.309-1.832-4.783-5.149,0.06-8.995c2.896-2.293,5.18,6.207,7.961,3.516c3.523-2.737-7.717-7.369,0.117-11.736 C473.413,240.77,480.519,242.891,482.414,245.296z"/> Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • plasma membrane
  • cytoplasm
  • extracellular
  • golgi
  • vesicle
  • cytoskeleton
  • endoplasmic reticulum
  • nucleus
  • endosome
  • lysosome
  • mitochondrion

Gene Ontology (GO) terms for PRY:

Related microRNA

Related microRNA

microRNAs potentially regulating PRY:     

Gene Interactions

Gene Interactions

Loading…
Interacting Gene Interaction Source/Score

Gene Pathways

Gene Pathways

Related Diseases

Related Diseases

Disease Score NofPmids NofSnps Source
Disease Score NofPmids NofSnps Source
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Male infertility 0.000271442 1 0 BeFree

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