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PMID: 1004487 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Heat-sensitive DNA-binding activity of the cI product of bacteriophage lambda.

Molecular & general genetics : MGG ·Vol. 146 ·No. 3 ·1976-08-02 ·Pages 299-302

Mandal NC, Lieb M

Abstract

The binding of lambda gene cI product to lambda DNA was studied at temperatures from 0 degrees C to 46 degrees C. Binding activity of the products of cIts mutants was higher at 22 degrees C than at 0 degrees C, 26 degrees C or 30 degrees C. Both cI+ and cIts products lost DNA-binding activity at 46 degrees C, but after subsequent cooling to 22 degrees C, they regained 50-100% of their activity.

MeSH Terms
Cold Temperature Coliphages/metabolism DNA Viruses DNA, Viral/metabolism Hot Temperature Mutation Protein Binding Protein Biosynthesis Viral Proteins/metabolism
Chemicals
DNA, Viral Viral Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Mandal N C
Lieb M
References (13)
13 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00701254
Published
1976-08-02
Pages
299-302
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00701254
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