Abstract
The mechanisms by which enteropathogenic Escherichia coli (EPEC) mediates diarrhea remain a mystery. Recently a number of interesting and at times surprising results have come from studying EPEC interactions with host cells. Identification and characterization of bacterial factors, including Tir, EspA, EspB and EspD, and host responses have expanded our grasp of the diverse effects of EPEC on host cells.
MeSH Terms
Adhesins, Bacterial
Animals
Bacterial Adhesion/physiology
Bacterial Outer Membrane Proteins/chemistry,metabolism,physiology
Bacterial Proteins/chemistry,metabolism,physiology
Carrier Proteins
Cytokines/metabolism
Diarrhea/microbiology
Drosophila Proteins
Epithelial Cells/metabolism,microbiology
Escherichia coli/metabolism,pathogenicity
Escherichia coli Proteins
Homeodomain Proteins/metabolism,physiology
Humans
Molecular Chaperones/metabolism,physiology
Receptors, Cell Surface/physiology
Repressor Proteins/physiology
Signal Transduction
Transcription Factors
Virulence
Chemicals
Adhesins, Bacterial
Bacterial Outer Membrane Proteins
Bacterial Proteins
Carrier Proteins
CesD protein, E coli
Cytokines
Drosophila Proteins
EaeB protein, E coli
Escherichia coli Proteins
EspA protein, E coli
EspD protein, E coli
Homeodomain Proteins
Molecular Chaperones
Receptors, Cell Surface
Repressor Proteins
SycH protein, Yersinia
Tir protein, E coli
Transcription Factors
eve protein, Drosophila
eaeA protein, E coli
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
DeVinney R
Biotechnology Laboratory University of British Columbia Vancouver British Columbia V6T 1Z4 Canada.
Knoechel D G
Finlay B B