Home LiteratureArticle Details
PMID: 1011266 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Electrophoretically silent alleles in a finite population.

Journal of molecular evolution ·Vol. 8 ·No. 4 ·1976-12-30 ·Pages 381-5

Nei M, Chakraborty R

Abstract

The expected number of silent alleles in an electromorph is computed for various values of population size (N), mutation rate (u), and sample size (s) under the assumption of no selection. The proportion of alleles undetectable by electrophoresis is higher when Nu is large than when this is small. It is shown that an electromorph of high population frequency has more silent alleles than an electromorph of low frequency if the sample size is the same.

MeSH Terms
Alleles Electrophoresis Mutation Polymorphism, Genetic Proteins
Chemicals
Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Nei M
Chakraborty R
References (13)
13 references, click to expand
  1. Distribution of allelic frequencies in a finite population under stepwise production of neutral alleles.
    Proc Natl Acad Sci U S A. 1975 Jul;72(7):2761-4 PMID: 1058491
  2. THE NUMBER OF ALLELES THAT CAN BE MAINTAINED IN A FINITE POPULATION.
    Genetics. 1964 Apr;49:725-38 PMID: 14156929
  3. Genetic distance and electrophoretic identity of proteins between taxa.
    J Mol Evol. 1973 Nov 27;2(4):323-8 PMID: 4807198
  4. Simulation studies on electrophoretically detectable genetic variability in a finite population.
    Genetics. 1974 Mar;76(3):615-24 PMID: 4833580
  5. The sampling theory of selectively neutral alleles.
    Theor Popul Biol. 1972 Mar;3(1):87-112 PMID: 4667078
  6. Electrophoretic variation in enzymes.
    Science. 1965 Aug 27;149(3687):936-43 PMID: 5318249
  7. A model of mutation appropriate to estimate the number of electrophoretically detectable alleles in a finite population.
    Genet Res. 1973 Oct;22(2):201-4 PMID: 4777279
  8. The structures of cytochrome c and the rates of molecular evolution.
    J Mol Evol. 1971;1(1):26-45 PMID: 4377446
  9. The charge-state model of protein polymorphism in natural populations.
    J Mol Evol. 1975 Nov 4;6(3):149-63 PMID: 1206725
  10. Extraordinary incidence of electrophoretically silent genetic polymorphisms.
    Nature. 1972 Oct 20;239(5373):453-4 PMID: 4628134
  11. Polyallelic mutational equilibria.
    Genetics. 1975 Apr;79(4):681-91 PMID: 1132686
  12. Still more genetic variability in natural populations.
    Proc Natl Acad Sci U S A. 1973 Dec;70(12):3928-31 PMID: 4521219
  13. The study of genic variation by electrophoretic and heat denaturation techniques at the octanol dehydrogenase locus in members of the Drosophila virilis group.
    Genetics. 1975 Jul;(3):637-50 PMID: 1232029
Article Info
Journal
Journal of molecular evolution
Abbr.
J Mol Evol
ISSN
0022-2844
Published
1976-12-30
Pages
381-5
Language
English
Region
Germany
NLM ID
0360051
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]