Tunicamycin-resistant mutants and chromosomal locations of mutational sites in Bacillus subtilis.

Journal of bacteriology ·Vol. 136 ·No. 2 ·1978-11-00 ·Pages 818-21

Nomura S, Yamane K, Sasaki T, Yamasaki M, Tamura G, Maruo B

Abstract

The types of tunicamycin-resistant mutants of Bacillus subtilis were analyzed, and their mutational sites on the chromosome were mapped. A type 1 mutation that simultaneously expressed hyperproductivity of extracellular alpha-amylase was located close to amy E. Type 2 mutations were near aroI.

MeSH Terms

Bacillus subtilis/drug effects,genetics Chromosome Mapping Chromosomes, Bacterial Drug Resistance, Microbial Genes Glucosamine/analogs & derivatives Tunicamycin/pharmacology alpha-Amylases/biosynthesis

Chemicals

Tunicamycin alpha-Amylases Glucosamine

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Nomura S

Yamane K

Sasaki T

Yamasaki M

Tamura G

Maruo B

References (12)

12 references, click to expand

PREPARATION OF TRANSFORMING DEOXYRIBONUCLEIC ACID BY PHENOL TREATMENT.
Biochim Biophys Acta. 1963 Aug 20;72:619-29 PMID: 14071565
Isolation of mutants defective in alpha-amylase from Bacillus subtilis: genetic analyses.
J Bacteriol. 1974 Aug;119(2):416-24 PMID: 4212116
Purification and properties of a cross-reacting material related to -amylase and biochemical comparison with the parent -amylase.
Biochim Biophys Acta. 1973 Jan 25;295(1):323-40 PMID: 4630927
On the gene controlling the rate of amylase production in Bacillus subtilis.
Biochem Biophys Res Commun. 1968 Apr 19;31(2):182-7 PMID: 4968472
Chromosomal location of genes regulating resistance to bacteriophage in Bacillus subtilis.
J Bacteriol. 1969 Jun;98(3):1087-97 PMID: 4977981
Temperature-sensitive mutants of Bacillus subtilis. I. Multiforked replication and sequential transfer of DNA by a temperature-sensitive mutant.
Proc Natl Acad Sci U S A. 1970 Jan;65(1):206-13 PMID: 4984231
Tunicamycin, a new antibiotic. I. Isolation and characterization of tunicamycin.
J Antibiot (Tokyo). 1971 Apr;24(4):215-23 PMID: 5572750
Lipid intermediates in the biosynthesis of the linkage unit between teichoic acids and peptidoglycan.
FEBS Lett. 1978 Feb 15;86(2):193-200 PMID: 624402
Tunicamycin, an inhibitor of Bacillus peptidoglycan synthesis: a new site of inhibition.
Biochem Biophys Res Commun. 1975 Nov 3;67(1):16-21 PMID: 812492
Hyperproductivity of extracellular alpha-amylase by a tunicamycin resistant mutant of Bacillus subtilis.
Biochem Biophys Res Commun. 1976 May 3;70(1):125-31 PMID: 819016
Mapping of mutations affecting synthesis of exocellular enzymes in Bacillus subtilis. Identity of the sacUh, amyB and pap mutations.
Mol Gen Genet. 1976 Nov 17;148(3):281-5 PMID: 827683
Tunicamycin inhibition of bacterial wall polymer synthesis.
FEBS Lett. 1977;78(1):151-4 PMID: 872935

Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.136.2.818-821.1978

Published

1978-11-00

Pages

818-21

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC218613

Subset

External Links

PubMed source DOI: 10.1128/jb.136.2.818-821.1978 PMC Full Text View journal details

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Tunicamycin-resistant mutants and chromosomal locations of mutational sites in Bacillus subtilis.

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