Molecular insights into the physiology of the 'thin film' of airway surface liquid.

The Journal of physiology ·Vol. 516 ( Pt 3) ·1999-05-01 ·Pages 631-8

Boucher RC

Abstract

The epithelia that line the airways of the lung exhibit two general functions: (1) airway epithelia in all regions 'defend' the lung against infectious and noxious agents; and (2) airway epithelia in the proximal regions replenish water lost from airway surfaces, i.e. the 'insensible water loss', consequent to conditioning inspired air. How airway epithelia perform both functions, and co-ordinate them in health and disease, is the subject of this review.

MeSH Terms

Animals Epithelium/physiology Humans Lung/physiology Surface Properties

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Boucher R C

Cystic Fibrosis/Pulmonary Research and Treatment Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7248, USA. [email protected]

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Article Info

Journal

The Journal of physiology

Abbr.

J Physiol

ISSN

0022-3751

DOI

10.1111/j.1469-7793.1999.0631u.x

[email protected]

Published

1999-05-01

Pages

631-8

Language

English

Region

England

NLM ID

0266262

PMCID

PMC2269304

Subset

External Links

PubMed source DOI: 10.1111/j.1469-7793.1999.0631u.x PMC Full Text View journal details

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Molecular insights into the physiology of the 'thin film' of airway surface liquid.

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