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PMID: 10326541 Published · ppublish English Comparative Study Letter Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Heterozygote advantage of the MTHFR gene in patients with neural-tube defect and their relatives.

Lancet (London, England) ·Vol. 351 ·No. 9115 ·1998-05-23 ·Pages 1554-5

Weitkamp LR, Tackels DC, Hunter AG, Holmes LB, Schwartz CE

Abstract

暂无摘要

MeSH Terms

Abortion, Spontaneous/genetics Alleles Female Gene Frequency Genetic Predisposition to Disease Genetic Variation/genetics Genotype Heterozygote Homozygote Humans Male Methylenetetrahydrofolate Dehydrogenase (NAD+) Mutation/genetics Neural Tube Defects/enzymology,genetics Oxidoreductases/genetics Pregnancy Sex Factors Spinal Dysraphism/enzymology,genetics

Chemicals

Oxidoreductases Methylenetetrahydrofolate Dehydrogenase (NAD+)

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Weitkamp L R

Tackels D C

Hunter A G

Holmes L B

Schwartz C E

Article Info

Journal

Lancet (London, England)

Abbr.

Lancet

ISSN

0140-6736

DOI

10.1016/s0140-6736(05)61119-1

Published

1998-05-23

Pages

1554-5

Language

English

Region

England

NLM ID

2985213R

Subset

Grants

NICHD NIH HHS · HD-24560 · United States

PHS HHS · U85/CCU408774 · United States

External Links

PubMed source DOI: 10.1016/s0140-6736(05)61119-1 View journal details

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Heterozygote advantage of the MTHFR gene in patients with neural-tube defect and their relatives.

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