Mutation in the HNF-4alpha gene affects insulin secretion and triglyceride metabolism.

Aged Basic Helix-Loop-Helix Leucine Zipper Transcription Factors DNA-Binding Proteins Diabetes Mellitus, Type 2/blood,genetics,metabolism Female Hepatocyte Nuclear Factor 4 Humans Insulin/deficiency,metabolism Insulin Secretion Male Middle Aged Mutation/genetics,physiology Phosphoproteins/genetics Transcription Factors/genetics Triglycerides/blood

Basic Helix-Loop-Helix Leucine Zipper Transcription Factors DNA-Binding Proteins HNF4A protein, human Hepatocyte Nuclear Factor 4 Insulin MLX protein, human Phosphoproteins Transcription Factors Triglycerides