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PMID: 1035129 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Presence of cellular rentinol and retinoic acid binding proteins in experimental rumors.

Cancer letters ·Vol. 2 ·No. 1 ·1976-09-00 ·Pages 25-30

Ong DE, Chytil F

Abstract

Cellular retinol and retinoic acid binding proteins were detected in mouse skin papillomas, human adenocarcinoma HAD-1, Dunning Leukemia, Walker 256 carcinosarcoma and mammary adenocarcinoma MAC-1. A chondrosarcoma and Sarcoma 180 apparently contain only the cellular retinoic acid binding protein. Neither protein could be detected in Ehrlich carcinoma and L1210 leukemia. The presence of these proteins might be necessary for sensitivity to retinoid therapy.

MeSH Terms
Animals Humans Neoplasms, Experimental/analysis,drug therapy Retinol-Binding Proteins/analysis Tretinoin/metabolism,therapeutic use Vitamin A/metabolism,therapeutic use
Chemicals
Retinol-Binding Proteins Vitamin A Tretinoin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ong D E
Chytil F
Article Info
Journal
Cancer letters
Abbr.
Cancer Lett
ISSN
0304-3835
Published
1976-09-00
Pages
25-30
Language
English
Region
Ireland
NLM ID
7600053
Subset
IM
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