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PMID: 10354860 Published · ppublish English Case Reports Journal Article

Use of cerebrospinal fluid shunt for the management of elevated intracranial pressure in a patient with active AIDS-related cryptococcal meningitis.

Diagnostic microbiology and infectious disease ·Vol. 34 ·No. 2 ·1999-06-00 ·Pages 111-4

Mylonakis E, Merriman NA, Rich JD, Flanigan TP, Walters BC, Tashima KT, Mileno MD, van der Horst CM

Abstract

Persistently elevated intracranial pressure (ICP) is one of the most accurate predictors of a poor prognosis in patients with AIDS-related cryptococcal meningitis. We present a severe case of persistent cryptococcal meningitis in a patient with advanced AIDS, complicated by elevation of ICP. A ventriculoperitoneal shunt was placed that successfully lowered the ICP and alleviated the associated symptoms. The elevated ICP secondary to AIDS-related cryptococcal meningitis should be treated aggressively. Despite the risk of shunt complications, cerebrospinal fluid shunts can be considered in these patients if they do not respond to other treatment.

MeSH Terms
AIDS-Related Opportunistic Infections/microbiology,physiopathology,therapy Adult Humans Intracranial Pressure Male Meningitis, Cryptococcal/physiopathology,therapy Ventriculoperitoneal Shunt
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Mylonakis E
Department of Medicine, Miriam Hospital, Brown University School of Medicine, Providence, RI 02906, USA.
Merriman N A
Rich J D
Flanigan T P
Walters B C
Tashima K T
Mileno M D
van der Horst C M
Article Info
Journal
Diagnostic microbiology and infectious disease
Abbr.
Diagn Microbiol Infect Dis
ISSN
0732-8893
Published
1999-06-00
Pages
111-4
Language
English
Region
United States
NLM ID
8305899
Subset
IM
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