Targeted cross-linking and DNA cleavage within model chromatin complexes.

Amino Acid Substitution Animals Carbon Radioisotopes Cattle Chickens Chromatin/chemistry,metabolism Cloning, Molecular/methods Cross-Linking Reagents Cysteine DNA/metabolism DNA, Ribosomal/isolation & purification,metabolism Electrophoresis, Polyacrylamide Gel/methods Erythrocytes/metabolism Ethylmaleimide/pharmacokinetics Histones/chemistry,genetics,metabolism Indicators and Reagents Mutagenesis, Site-Directed Plasmids Polymerase Chain Reaction/methods RNA, Ribosomal, 5S/genetics Radioisotope Dilution Technique Recombinant Proteins/chemistry,isolation & purification,metabolism Xenopus

Carbon Radioisotopes Chromatin Cross-Linking Reagents DNA, Ribosomal Histones Indicators and Reagents RNA, Ribosomal, 5S Recombinant Proteins DNA Cysteine Ethylmaleimide