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PMID: 10393865 Published · ppublish English Comment Journal Article Review

Postmitochondrial regulation of apoptosis during heart failure.

Reed JC, Paternostro G

Abstract

暂无摘要

MeSH Terms
Animals Apoptosis Cardiomyopathies/pathology,physiopathology Cardiomyopathy, Dilated/pathology,physiopathology Caspase 3 Caspases/metabolism Cytochrome c Group/metabolism Heart/physiopathology Homeostasis Humans Mitochondria, Heart/metabolism Myocardium/metabolism,pathology
Chemicals
Cytochrome c Group CASP3 protein, human Caspase 3 Caspases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Reed J C
The Burnham Institute, Program on Apoptosis and Cell Death Regulation, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. [email protected]
Paternostro G
References (57)
57 references, click to expand
  1. Interaction and regulation of subcellular localization of CED-4 by CED-9.
    Science. 1997 Feb 21;275(5303):1126-9 PMID: 9027313
  2. Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death.
    J Biol Chem. 1998 Dec 4;273(49):32479-86 PMID: 9829980
  3. Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy.
    Proc Natl Acad Sci U S A. 1999 Jul 6;96(14):8144-9 PMID: 10393962
  4. Apoptosis in the failing human heart.
    N Engl J Med. 1997 Apr 17;336(16):1131-41 PMID: 9099657
  5. Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis.
    J Exp Med. 1996 Dec 1;184(6):2399-404 PMID: 8976194
  6. A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis.
    J Biol Chem. 1999 Jan 22;274(4):2072-6 PMID: 9890966
  7. Reperfusion injury induces apoptosis in rabbit cardiomyocytes.
    J Clin Invest. 1994 Oct;94(4):1621-8 PMID: 7929838
  8. Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c.
    Nature. 1998 Jan 29;391(6666):496-9 PMID: 9461218
  9. Mitochondria as regulators of apoptosis: doubt no more.
    Biochim Biophys Acta. 1998 Aug 10;1366(1-2):151-65 PMID: 9714783
  10. X-linked IAP is a direct inhibitor of cell-death proteases.
    Nature. 1997 Jul 17;388(6639):300-4 PMID: 9230442
  11. Mitochondrial release of caspase-2 and -9 during the apoptotic process.
    J Exp Med. 1999 Jan 18;189(2):381-94 PMID: 9892620
  12. Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease.
    Circ Res. 1998 Jul 27;83(2):117-32 PMID: 9686751
  13. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond.
    Trends Biochem Sci. 1997 Sep;22(9):355-8 PMID: 9301337
  14. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis.
    Science. 1997 Feb 21;275(5303):1132-6 PMID: 9027315
  15. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3.
    Cell. 1997 Aug 8;90(3):405-13 PMID: 9267021
  16. Granzyme release and caspase activation in activated human T-lymphocytes.
    J Biol Chem. 1998 Mar 20;273(12):6916-20 PMID: 9506996
  17. BAG-1 modulates the chaperone activity of Hsp70/Hsc70.
    EMBO J. 1997 Aug 15;16(16):4887-96 PMID: 9305631
  18. mE10, a novel caspase recruitment domain-containing proapoptotic molecule.
    J Biol Chem. 1999 Apr 9;274(15):10287-92 PMID: 10187815
  19. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c.
    Cell. 1996 Jul 12;86(1):147-57 PMID: 8689682
  20. Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis.
    Cancer Res. 1999 Mar 1;59(5):999-1002 PMID: 10070954
  21. Human skeletal muscle cytosols are refractory to cytochrome c-dependent activation of type-II caspases and lack APAF-1.
    Cell Death Differ. 1999 Mar;6(3):256-61 PMID: 10200576
  22. The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event.
    J Cell Biol. 1999 Mar 8;144(5):883-9 PMID: 10085288
  23. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
    Cell. 1997 Nov 14;91(4):479-89 PMID: 9390557
  24. Bcl-2 regulates amplification of caspase activation by cytochrome c.
    Curr Biol. 1999 Feb 11;9(3):147-50 PMID: 10021389
  25. Regulation of cell death protease caspase-9 by phosphorylation.
    Science. 1998 Nov 13;282(5392):1318-21 PMID: 9812896
  26. An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9.
    J Biol Chem. 1999 Apr 23;274(17):11549-56 PMID: 10206961
  27. Bcl-2 family proteins as ion-channels.
    Cell Death Differ. 1998 May;5(5):372-80 PMID: 10200486
  28. ATP-dependent steps in apoptotic signal transduction.
    Cancer Res. 1999 May 1;59(9):2174-81 PMID: 10232605
  29. Apoptosis in myocytes in end-stage heart failure.
    N Engl J Med. 1996 Oct 17;335(16):1182-9 PMID: 8815940
  30. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell.
    J Clin Invest. 1998 Apr 1;101(7):1326-42 PMID: 9525975
  31. Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation.
    Biochem Biophys Res Commun. 1997 Nov 17;240(2):419-24 PMID: 9388494
  32. Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity.
    Cell. 1995 Jan 27;80(2):279-84 PMID: 7834747
  33. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases.
    EMBO J. 1997 Dec 1;16(23):6914-25 PMID: 9384571
  34. Proteases to die for.
    Genes Dev. 1998 Jun 1;12(11):1551-70 PMID: 9620844
  35. Genetics of programmed cell death in C. elegans: past, present and future.
    Trends Genet. 1998 Oct;14(10):410-6 PMID: 9820030
  36. Molecular characterization of mitochondrial apoptosis-inducing factor.
    Nature. 1999 Feb 4;397(6718):441-6 PMID: 9989411
  37. Release of cytochrome c from heart mitochondria is induced by high Ca2+ and peroxynitrite and is responsible for Ca(2+)-induced inhibition of substrate oxidation.
    Biochim Biophys Acta. 1999 Jan 6;1453(1):41-8 PMID: 9989244
  38. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked.
    Science. 1997 Feb 21;275(5303):1129-32 PMID: 9027314
  39. CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor.
    EMBO J. 1998 May 1;17(9):2526-33 PMID: 9564035
  40. Caspases: intracellular signaling by proteolysis.
    Cell. 1997 Nov 14;91(4):443-6 PMID: 9390553
  41. Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death.
    Science. 1997 Feb 21;275(5303):1122-6 PMID: 9027312
  42. Cytochrome c release from brain mitochondria is independent of the mitochondrial permeability transition.
    FEBS Lett. 1998 Nov 20;439(3):373-6 PMID: 9845356
  43. Fas-induced caspase denitrosylation.
    Science. 1999 Apr 23;284(5414):651-4 PMID: 10213689
  44. Overexpression of Bax protein and enhanced apoptosis in the left ventricle of spontaneously hypertensive rats: effects of AT1 blockade with losartan.
    Hypertension. 1998 Aug;32(2):280-6 PMID: 9719055
  45. Boo, a novel negative regulator of cell death, interacts with Apaf-1.
    EMBO J. 1999 Jan 4;18(1):167-78 PMID: 9878060
  46. Interaction between the C. elegans cell-death regulators CED-9 and CED-4.
    Nature. 1997 Feb 13;385(6617):653-6 PMID: 9024666
  47. Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases.
    EMBO J. 1998 Nov 2;17(21):6124-34 PMID: 9799222
  48. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases.
    EMBO J. 1998 Apr 15;17(8):2215-23 PMID: 9545235
  49. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.
    Cell. 1997 Apr 18;89(2):175-84 PMID: 9108473
  50. X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
    Nature. 1996 May 23;381(6580):335-41 PMID: 8692274
  51. Mitochondria and apoptosis.
    Science. 1998 Aug 28;281(5381):1309-12 PMID: 9721092
  52. Bax directly induces release of cytochrome c from isolated mitochondria.
    Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):4997-5002 PMID: 9560217
  53. Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types.
    Cell. 1999 Jan 8;96(1):35-45 PMID: 9989495
  54. Do all programmed cell deaths occur via apoptosis?
    Proc Natl Acad Sci U S A. 1993 Feb 1;90(3):980-4 PMID: 8430112
  55. The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling.
    J Cell Biol. 1998 Mar 23;140(6):1485-95 PMID: 9508780
  56. Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia.
    Proc Natl Acad Sci U S A. 1999 May 11;96(10):5752-7 PMID: 10318956
  57. The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death.
    Dev Biol. 1990 Mar;138(1):33-41 PMID: 2307287
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1999-07-06
Pages
7614-6
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC33586
Subset
IM
Corrections
CommentOn
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