In vitro activity of penicillins against anaerobes.

Antimicrobial agents and chemotherapy ·Vol. 7 ·No. 4 ·1975-04-00 ·Pages 413-4

Tally FP, Jacobus NV, Bartlett JG, Gorbach SL

Abstract

The in vitro susceptibility of 162 anaerobic isolates from clinical material were tested to pencillin G, BL-P1654, and carbenicillin. Penicillin G and BL-P1654 showed good activity against Bacteroides fragilis, but only 60% of strains were susceptible to carbenicillin at achievable blood levels (128 mug/ml).

MeSH Terms

Anaerobiosis Bacteria/drug effects Penicillin Resistance Penicillins/pharmacology

Chemicals

Penicillins

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Tally F P

Jacobus N V

Bartlett J G

Gorbach S L

References (9)

9 references, click to expand

Anaerobic infections. 1.
N Engl J Med. 1974 May 23;290(21):1177-84 PMID: 4824012
The susceptibility of Bacteroides fragilis to 24 antibiotics.
J Infect Dis. 1972 Mar;125(3):295-9 PMID: 4335792
Antibiotic sensitivity testing. Report of an international collaborative study.
Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;217:Suppl 217:1+ PMID: 4325956
Diagnosis and management of infections associated with immunosuppression. New antibiotics of potential importance for immunosuppressed patients.
Transplant Proc. 1973 Sep;5(3):1227-31 PMID: 4199578
Anaerobic infections of the female genital tract: bacteriologic and therapeutic aspects.
Am J Obstet Gynecol. 1973 Dec 15;117(8):1034-40 PMID: 4586019
Diagnostic features of clindamycin-associated pseudomembranous colitis.
N Engl J Med. 1974 Apr 11;290(15):841-3 PMID: 4855527
In vitro antimicrobial susceptibility of anaerobic bacteria isolated from clinical specimens.
Antimicrob Agents Chemother. 1972 Feb;1(2):148-58 PMID: 4680804
The susceptibility of bacteroides to the penicillins and cephalothin.
Am J Med Sci. 1966 Apr;251(4):428-32 PMID: 5910227
Antibiotic susceptibility testing of Bacteroides.
Antimicrob Agents Chemother. 1972 Aug;2(2):57-60 PMID: 4670488

Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.7.4.413

Published

1975-04-00

Pages

413-4

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC429153

Subset

External Links

PubMed source DOI: 10.1128/AAC.7.4.413 PMC Full Text View journal details

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In vitro activity of penicillins against anaerobes.

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