Genetic control of the immune response to the GAT terpolymer. I. Interstrain and interspecies cross-reactive idiotype.

Annales d'immunologie ·Vol. 129 C ·No. 5 ·1978-00-00 ·Pages 721-6

Thèze J, Moreau JL

Abstract

An antiidiotypic antiserum specific for the GAT antibodies of BALB/c mice has been obtained in rabbits. This serum recognizes the GAT idiotype of 13 inbred strains of mice as well as the GAT idiotype present in sera of guinea-pigs, rats and rabbits immunized with GAT. Such an antiidiotypic antiserum should serve as a good reagent to detect putative idiotypic determinants on GAT-specific suppressor factor.

MeSH Terms

Animals Antibody Specificity Cross Reactions Genes, MHC Class II Guinea Pigs Immune Sera Immunoglobulin Idiotypes Mice Mice, Inbred BALB C/immunology Mice, Inbred Strains/immunology Peptides/immunology Rabbits Rats Species Specificity

Chemicals

Immune Sera Immunoglobulin Idiotypes Peptides

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Thèze J

Moreau J L

Article Info

Journal

Annales d'immunologie

Abbr.

Ann Immunol (Paris)

ISSN

0300-4910

Published

1978-00-00

Pages

721-6

Language

English

Region

France

NLM ID

0353045

Subset

External Links

PubMed source

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Genetic control of the immune response to the GAT terpolymer. I. Interstrain and interspecies cross-reactive idiotype.

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