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PMID: 10489957 Published · ppublish English Letter Research Support, Non-U.S. Gov't

Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease.

Lancet (London, England) ·Vol. 354 ·No. 9182 ·1999-09-11 ·Pages 919-20

Esiri MM, Nagy Z, Smith MZ, Barnetson L, Smith AD

Abstract

Cerebrovascular disease and Alzheimer's disease commonly occur together in the elderly and each may contribute to dementia. Here we present evidence that cerebrovascular disease significantly worsens cognitive performance in the earliest stages of Alzheimer's disease.

MeSH Terms

Aged Alzheimer Disease/diagnosis,pathology Brain/pathology Brain Mapping Cerebrovascular Disorders/diagnosis,pathology Cohort Studies Dementia, Vascular/diagnosis,pathology Female Humans Longitudinal Studies Male Neuropsychological Tests Risk Factors

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Esiri M M

Nagy Z

Smith M Z

Barnetson L

Smith A D

Article Info

Journal

Lancet (London, England)

Abbr.

Lancet

ISSN

0140-6736

DOI

10.1016/S0140-6736(99)02355-7

Published

1999-09-11

Pages

919-20

Language

English

Region

England

NLM ID

2985213R

Subset

External Links

PubMed source DOI: 10.1016/S0140-6736(99)02355-7 View journal details

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Cerebrovascular disease and threshold for dementia in the early stages of Alzheimer's disease.

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