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PMID: 10508507 Published · ppublish English Letter

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia.

Nature genetics ·Vol. 23 ·No. 2 ·1999-10-00 ·Pages 144-6

Castilla LH, Garrett L, Adya N, Orlic D, Dutra A, Anderson S, Owens J, Eckhaus M, Bodine D, Liu PP

Abstract

暂无摘要

MeSH Terms
Animals Cell Differentiation/genetics Ethylnitrosourea/adverse effects Genetic Predisposition to Disease Granulocytes/cytology Hematopoiesis/genetics Leukemia, Myelomonocytic, Acute/chemically induced,genetics Mice Mice, Inbred C57BL Mice, Inbred Strains Mutagens/adverse effects Oncogene Proteins, Fusion/genetics
Chemicals
CBFbeta-MYH11 fusion protein Mutagens Oncogene Proteins, Fusion Ethylnitrosourea
Authors & Affiliations
10 authors, click to expand affiliations / ORCID
Castilla L H
Garrett L
Adya N
Orlic D
Dutra A
Anderson S
Owens J
Eckhaus M
Bodine D
Liu P P
Article Info
Journal
Nature genetics
Abbr.
Nat Genet
ISSN
1061-4036
DOI
10.1038/13776
Published
1999-10-00
Pages
144-6
Language
English
Region
United States
NLM ID
9216904
Subset
IM
External Links
PubMed source DOI: 10.1038/13776 View journal details
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