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PMID: 10515949 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Porins in the cell wall of Mycobacterium tuberculosis.

Journal of bacteriology ·Vol. 181 ·No. 20 ·1999-10-00 ·Pages 6543-6

Kartmann B, Stenger S, Niederweis M, Stengler S

Abstract

Lipid bilayer experiments indicated that the cell wall of Mycobacterium tuberculosis contains at least two different porins: (i) a cation-selective, heat-sensitive 0.7-nS channel which has a short-lived open state and is probably composed of 15-kDa subunits and (ii) a 3-nS, >60-kDa channel with a long-lived open state, resembling porins from fast-growing mycobacteria.

MeSH Terms
Cations, Monovalent/metabolism Cell Compartmentation Cell Wall/chemistry,metabolism Diffusion Electric Conductivity Ion Channel Gating Liposomes Mycobacterium tuberculosis/chemistry,metabolism Porins/isolation & purification,metabolism Protein Structure, Quaternary
Chemicals
Cations, Monovalent Liposomes Porins mspA protein, Mycobacterium smegmatis
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Kartmann B
Lehrstuhl für Mikrobiologie, Immunologie und Hygiene, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Stenger S
Niederweis M
Stengler S
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/JB.181.20.6543-6546.1999
Published
1999-10-00
Pages
6543-6
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC103794
Subset
IM
Grants
NIAID NIH HHS · N01-AI-75320 · United States
Corrections
ErratumIn
-
External Links
PubMed source DOI: 10.1128/JB.181.20.6543-6546.1999 PMC Full Text View journal details
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