Lambda repressor turns off transcription of its own gene.
We report transcription in vitro of the lambda repressor gene, cI, using specific restriction endonuclease fragments as templates. This transcription is repressed by lambda repressor. Moreover, we report the sequence change caused by a cI promoter mutation. This change is located between two repressor binding sites in the rightward operator (OR). Transcription studies using mutant templates indicate that repressor bound to two sites in OR regulates transcription of gene tof, and repressor bound to the remaining site(s) controls transcription of cI.
20 references, click to expand
-
In vitro repression of RNA synthesis by purified lambda phage repressor.Nat New Biol. 1971 Mar 17;230(11):76-80 PMID: 5279042
-
Control elements in the DNA of bacteriophage lambda.Cold Spring Harb Symp Quant Biol. 1974;38:857-68 PMID: 4545512
-
Sequence of the PR promoter of phage lambda.Nature. 1975 Mar 13;254(5496):118-21 PMID: 1117996
-
Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda.Cell. 1975 Jun;5(2):109-13 PMID: 1095210
-
Genetic characterization of a prm- mutant of bacteriophage lambda.Virology. 1973 Nov;56(1):300-12 PMID: 4583306
-
Structure of the lambda operators.Nature. 1973 Nov 16;246(5429):133-6 PMID: 4586104
-
The nucleotide sequence of the lactose messenger ribonucleic acid transcribed from the UV5 promoter mutant of Escherichia coli.Proc Natl Acad Sci U S A. 1973 Dec;70(12):3585-9 PMID: 4587256
-
Multiple repressor binding at the operators in bacteriophage lambda.Proc Natl Acad Sci U S A. 1973 May;70(5):1531-5 PMID: 4514322
-
Mutations in the right operator of bacteriophage lambda: evidence for operator-promoter interpenetration.J Mol Biol. 1973 Oct 5;79(4):709-22 PMID: 4758068
-
Termination factor for RNA synthesis.Nature. 1969 Dec 20;224(5225):1168-74 PMID: 4902144
-
Effect of ultraviolet irradiation on bacteriophage lambda immunity.J Mol Biol. 1967 Jan 28;23(2):247-63 PMID: 5340187
-
Repression and autogenous stimulation in vitro by bacteriophage lambda repressor.Proc Natl Acad Sci U S A. 1975 Mar;72(3):804-8 PMID: 1055378
-
Control of bacteriophage lambda repressor synthesis: regulation of the maintenance pathway of the cro and cI products.J Mol Biol. 1975 Apr 5;93(2):289-309 PMID: 1152054
-
Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis.Biochemistry. 1975 Aug 26;14(17):3787-94 PMID: 1174504
-
The operators controlled by the lambda phage repressor.Proc Natl Acad Sci U S A. 1968 Aug;60(4):1282-7 PMID: 5244737
-
Asymmetric distribution of the transcribing regions on the complementary strands of coliphage lambda DNA.Proc Natl Acad Sci U S A. 1967 Jun;57(6):1618-25 PMID: 5231395
-
Nucleotide sequence of the rightward operator of phage lambda.Proc Natl Acad Sci U S A. 1975 Mar;72(3):1184-8 PMID: 1055375
-
Separation and analysis of promoter sites in bacteriophage lambda DNA by specific endonucleases.J Mol Biol. 1974 Jan 5;85(4):475-84 PMID: 4546908
-
Promoters are in the operators in phage lambda.Nature. 1974 May 17;249(454):221-3 PMID: 4598033
-
RNA synthesis startpoints in bacteriophage lambda: are the promoter and operator transcribed?Nat New Biol. 1972 Jun 21;237(77):227-32 PMID: 4556643
Contact
No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong
Qilu Normal University · Genelibs Bioinformatics Lab
750 Shunhua Rd, Jinan
2F, Bldg F, University Science Park
Tel: 0531-88819269
WeChat Official Account
Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.
Business Email
E-mail: [email protected]
Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2
