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PMID: 10611270 Published · ppublish English Comment Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

How many mutations does it take to make a tumor?

Boland CR, Ricciardiello L

Abstract

暂无摘要

MeSH Terms
Adenomatous Polyps/etiology,genetics Cell Transformation, Neoplastic/genetics Colorectal Neoplasms/etiology,genetics Humans Loss of Heterozygosity Models, Genetic Mutation
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Boland C R
Department of Medicine, University of California, San Diego, CA 92093-0688, USA. [email protected]
Ricciardiello L
References (18)
18 references, click to expand
  1. The onset and extent of genomic instability in sporadic colorectal tumor progression.
    Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):15121-6 PMID: 10611348
  2. Creation of human tumour cells with defined genetic elements.
    Nature. 1999 Jul 29;400(6743):464-8 PMID: 10440377
  3. Genetic alterations during colorectal-tumor development.
    N Engl J Med. 1988 Sep 1;319(9):525-32 PMID: 2841597
  4. Allelotype of colorectal carcinomas.
    Science. 1989 Apr 14;244(4901):207-11 PMID: 2565047
  5. Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction.
    Proc Natl Acad Sci U S A. 1992 Nov 1;89(21):10065-9 PMID: 1359533
  6. Genetic mapping of a locus predisposing to human colorectal cancer.
    Science. 1993 May 7;260(5109):810-2 PMID: 8484120
  7. Clues to the pathogenesis of familial colorectal cancer.
    Science. 1993 May 7;260(5109):812-6 PMID: 8484121
  8. Microsatellite instability in cancer of the proximal colon.
    Science. 1993 May 7;260(5109):816-9 PMID: 8484122
  9. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis.
    Nature. 1993 Jun 10;363(6429):558-61 PMID: 8505985
  10. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.
    Cell. 1993 Dec 3;75(5):1027-38 PMID: 8252616
  11. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer.
    Cell. 1993 Dec 17;75(6):1215-25 PMID: 8261515
  12. Microsatellite instability: marker of a mutator phenotype in cancer.
    Cancer Res. 1994 Oct 1;54(19):5059-63 PMID: 7923117
  13. Microallelotyping defines the sequence and tempo of allelic losses at tumour suppressor gene loci during colorectal cancer progression.
    Nat Med. 1995 Sep;1(9):902-9 PMID: 7585215
  14. Genomic instability in sporadic colorectal cancer quantitated by inter-simple sequence repeat PCR analysis.
    Genes Chromosomes Cancer. 1997 Jan;18(1):19-29 PMID: 8993977
  15. Genetic instability in colorectal cancers.
    Nature. 1997 Apr 10;386(6625):623-7 PMID: 9121588
  16. Mutations of mitotic checkpoint genes in human cancers.
    Nature. 1998 Mar 19;392(6673):300-3 PMID: 9521327
  17. Molecular karyotype (amplotype) of metastatic colorectal cancer by unbiased arbitrarily primed PCR DNA fingerprinting.
    Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10170-5 PMID: 9707619
  18. JC virus DNA is present in the mucosa of the human colon and in colorectal cancers.
    Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7484-9 PMID: 10377441
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1999-12-21
Pages
14675-7
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC33954
Subset
IM
Grants
NCI NIH HHS · R01 CA072851 · United States
NCI NIH HHS · CA72851 · United States
Corrections
CommentOn
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