Home LiteratureArticle Details
PMID: 1062803 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

The partial amino-acid sequence of an H-2K molecule.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 73 ·No. 3 ·1976-03-00 ·Pages 905-9

Vitetta ES, Capra JD, Klapper DG, Klein J, Uhr JW

Abstract

Eighteen of the NH2-terminal 27 amino acids of a murine H-2K molecule have been assigned. The approach used was to label murine splenocytes with a single radioactive amino acid, isolate the H-2K molecule by specific immunoprecipitation, electrophorese the dissolved precipitate on sodium dodecyl sulfate polyacrylamide gels, and subject the isolated H-2K peak to amino-acid analysis and automated sequencing.

MeSH Terms
Amino Acid Sequence Animals Histocompatibility Antigens/analysis Isoantibodies Mice Spleen/immunology
Chemicals
Histocompatibility Antigens Isoantibodies
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Vitetta E S
Capra J D
Klapper D G
Klein J
Uhr J W
References (27)
27 references, click to expand
  1. The somatic generation of immune recognition.
    Eur J Immunol. 1971 Jan;1(1):1-9 PMID: 14978855
  2. The Antigens Determined by the H-2 Locus: A Rhesus-Like System in the Mouse.
    Proc Natl Acad Sci U S A. 1954 Nov;40(11):1040-51 PMID: 16578433
  3. An analysis of an antigenic system in the mouse (the H-2 system).
    Proc R Soc Lond B Biol Sci. 1955 Nov 29;144(916):369-80 PMID: 13280688
  4. Isolation of H-2 alloantigens solubilized by the detergent NP-40.
    J Immunol. 1971 Nov;107(5):1363-7 PMID: 5171127
  5. Reversible denaturation of enzymes by sodium dodecyl sulfate.
    J Biol Chem. 1971 Jul 25;246(14):4504-9 PMID: 5106387
  6. Isolation of heavy and light chains of immunoglobulin from the surfaces of lymphoid cells.
    J Immunol. 1971 Apr;106(4):1133-5 PMID: 5553716
  7. The genetic control of immunoglobulin synthesis.
    Annu Rev Genet. 1972;6:1-46 PMID: 4124595
  8. Detergent-solubilised H-2 alloantigen is associated with a small molecular weight polypeptide.
    Nature. 1974 Jun 21;249(459):764-5 PMID: 4134396
  9. Membrane molecules determined by the H-2 associated immune response region: isolation and some properties.
    Proc Natl Acad Sci U S A. 1974 Mar;71(3):648-52 PMID: 4132532
  10. Isoelectric focusing of proteins exposed to sodium dodecyl sulfate.
    Anal Biochem. 1974 Jul;60(1):142-8 PMID: 4136838
  11. Isolation and properties of a low molecular weight beta-2-globulin occurring in human biological fluids.
    J Biol Chem. 1968 Aug 10;243(15):4095-103 PMID: 4175239
  12. Amino acid sequence similarities in two human anti gamma globulin antibodies.
    Proc Natl Acad Sci U S A. 1970 Sep;67(1):87-92 PMID: 4195825
  13. Synthesis, intracellular distribution, and secretion of immunoglobulin and H-2 antigen in muring splenocytes.
    J Exp Med. 1973 Oct 1;138(4):847-57 PMID: 4200648
  14. Association of a beta2-microglobulin-like subunit with H-2 and TL alloantigens on murine thymocytes.
    J Immunol. 1975 Jan;114(1 Pt 1):252-4 PMID: 46243
  15. Biochemical properties and immunochemical-genetic relationships of mouse H-2 alloantigens.
    Biochim Biophys Acta. 1974 Apr 8;344(1):1-25 PMID: 4598853
  16. Induction of resistance to antibody-mediated cytotoxicity. H-2, Ia, and Ig antigens are independent entities in the membrane of mouse lymphocytes.
    J Exp Med. 1975 May 1;141(5):1047-56 PMID: 47892
  17. Structural studies on induced antibodies with defined idiotypic specificities. II. The light chains of anti-p-azophenylarsonate antibodies from A/J mice bearing a cross-reactive idiotype.
    J Immunol. 1975 Aug;115(2):414-8 PMID: 1151064
  18. Synthesis of surface H-2 alloantigens in murine splenocytes.
    J Immunol. 1975 Aug;115(2):374-81 PMID: 1151063
  19. Protein sequencing: thermal conversion of thiazolinone derivatives of amino acids to thiohydantoins.
    Anal Biochem. 1975 Jun;66(2):400-4 PMID: 1169891
  20. An approach to amino acid sequence analysis of transplantation antigens.
    Nature. 1975 Jul 3;256(5512):63-4 PMID: 1134585
  21. Molecular relationship between private and public H-2 antigens as determined by antigen redistribution method.
    J Exp Med. 1975 Aug 1;142(2):288-98 PMID: 49386
  22. Evolution of neurophysin proteins: the partial sequence of bovine neurophysin-I (vasopressin-oxytocin-carrier proteins-automated amino-acid-sequence analysis-homology-protein evolution).
    Proc Natl Acad Sci U S A. 1972 Feb;69(2):431-4 PMID: 4501123
  23. The 11,000-dalton component of mouse H-2. Isolation and identification.
    Transplantation. 1974 Dec;18(6):550-5 PMID: 4439455
  24. Amino acid sequence determination with radioactive proteins.
    Biochemistry. 1974 Jul 16;13(15):3048-51 PMID: 4841052
  25. Subunit structure of H-2 alloantigens.
    Nature. 1974 Jun 28;249(460):833-4 PMID: 4834787
  26. Private and public antigens of the mouse H-2 system.
    Nature. 1971 Feb 26;229(5287):635-7 PMID: 4925469
  27. Structural similarities between a product of the T/t-locus isolated from sperm and teratoma cells, and H-2 antigens isolated from splenocytes.
    Proc Natl Acad Sci U S A. 1975 Aug;72(8):3215-9 PMID: 1059107
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.73.3.905
Published
1976-03-00
Pages
905-9
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC336028
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.73.3.905 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2