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PMID: 10656987 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.

Biochimica et biophysica acta ·Vol. 1470 ·No. 1 ·2000-02-14 ·Pages M21-35

Vazquez F, Sellers WR

Abstract

暂无摘要

MeSH Terms

Animals Apoptosis/drug effects Cell Cycle/drug effects Enzyme Activation Focal Adhesion Protein-Tyrosine Kinases Genes, Tumor Suppressor Germ-Line Mutation Neoplasms/genetics PTEN Phosphohydrolase Phosphatidylinositol 3-Kinases/chemistry,metabolism Phosphoinositide-3 Kinase Inhibitors Phosphoric Monoester Hydrolases/genetics,metabolism,pharmacology Phosphorylation Protein Serine-Threonine Kinases/genetics,metabolism Protein-Tyrosine Kinases/antagonists & inhibitors Proto-Oncogene Proteins Proto-Oncogene Proteins c-akt Signal Transduction/drug effects Structure-Activity Relationship Tumor Suppressor Proteins

Chemicals

Phosphoinositide-3 Kinase Inhibitors Proto-Oncogene Proteins Tumor Suppressor Proteins Protein-Tyrosine Kinases Focal Adhesion Protein-Tyrosine Kinases Protein Serine-Threonine Kinases Proto-Oncogene Proteins c-akt Phosphoric Monoester Hydrolases PTEN Phosphohydrolase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Vazquez F

Department of Adult Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Sellers W R

Article Info

Journal

Biochimica et biophysica acta

Abbr.

Biochim Biophys Acta

ISSN

0006-3002

DOI

10.1016/s0304-419x(99)00032-3

Published

2000-02-14

Pages

M21-35

Language

English

Region

Netherlands

NLM ID

0217513

Subset

External Links

PubMed source DOI: 10.1016/s0304-419x(99)00032-3

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The PTEN tumor suppressor protein: an antagonist of phosphoinositide 3-kinase signaling.

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