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PMID: 10679312 Published · ppublish English Journal Article

Epstein-Barr virus: Co-opting B-cell memory and migration.

Current biology : CB ·Vol. 10 ·No. 3 ·2000-02-10 ·Pages R120-3

Rickinson AB, Lane PJ

Abstract

Epstein-Barr virus, a B-lymphotropic human herpesvirus, persists in vivo by entering the long-lived memory B-cell compartment. Work with genetically modified mice suggests that the viral latent membrane protein LMP1 might allow infected B cells to access the memory compartment by an unusual route.

MeSH Terms
Animals B-Lymphocytes/immunology,virology Cell Movement Epstein-Barr Virus Infections/immunology,virology Herpesvirus 4, Human/pathogenicity,physiology Humans Immunologic Memory Mice Viral Matrix Proteins/genetics,metabolism
Chemicals
EBV-associated membrane antigen, Epstein-Barr virus Viral Matrix Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Rickinson A B
CRC Institute for Cancer Studies, MRC Centre for Immune Regulation, University of Birmingham, Edgbaston, B15 2TT, UK. [email protected]
Lane P J
Article Info
Journal
Current biology : CB
Abbr.
Curr Biol
ISSN
0960-9822
DOI
10.1016/s0960-9822(00)00308-0
Email
[email protected]
Published
2000-02-10
Pages
R120-3
Language
English
Region
England
NLM ID
9107782
Subset
IM
External Links
PubMed source DOI: 10.1016/s0960-9822(00)00308-0 View journal details
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