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PMID: 10679317 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Intracellular signalling: Is PIP(2) a messenger too?

Current biology : CB ·Vol. 10 ·No. 3 ·2000-02-10 ·Pages R104-5

Hinchliffe K

Abstract

The phospholipid phosphatidylinositol (4,5) bisphosphate (PIP(2)) has recently been shown to act downstream of the small G proteins Rac and Arf. Different effectors may be employed in each case, suggesting that PIP(2) has multiple signalling roles.

MeSH Terms
ADP-Ribosylation Factors/metabolism Animals Cattle GTP-Binding Proteins/metabolism Phosphatidylinositol 4,5-Diphosphate/metabolism Phosphotransferases (Alcohol Group Acceptor)/metabolism Signal Transduction rac GTP-Binding Proteins/metabolism
Chemicals
Phosphatidylinositol 4,5-Diphosphate Phosphotransferases (Alcohol Group Acceptor) 1-phosphatidylinositol-4-phosphate 5-kinase GTP-Binding Proteins ADP-Ribosylation Factors rac GTP-Binding Proteins
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Hinchliffe K
Department of Pharmacology, University of Cambridge, Cambridge, CB2 1QJ, UK. [email protected]
Article Info
Journal
Current biology : CB
Abbr.
Curr Biol
ISSN
0960-9822
DOI
10.1016/s0960-9822(00)00303-1
Email
[email protected]
Published
2000-02-10
Pages
R104-5
Language
English
Region
England
NLM ID
9107782
Subset
IM
External Links
PubMed source DOI: 10.1016/s0960-9822(00)00303-1 View journal details
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