To check the anti-apoptosis gene bcl-2 mRNA expression in 20 APL patients by PCR, and analyse the relationship between bcl-2 mRNA and the PML-RARa isoform. The result is that the bcl-2 mRNA expression has no significance between the isoforms (P > 0.05). This shows that the PML-RARa transcription type has no influence on the clinical features and prognosis.
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