The PPARs: from orphan receptors to drug discovery.

Animals Diabetes Mellitus/drug therapy,metabolism Drug Design Humans Hyperlipidemias/drug therapy,metabolism Hypertension/drug therapy,metabolism Inflammation/drug therapy,metabolism Ligands Models, Molecular Neoplasms/drug therapy,metabolism Nuclear Proteins/physiology Obesity/drug therapy,metabolism Receptors, Cytoplasmic and Nuclear/chemistry,drug effects,metabolism,physiology Transcription Factors/chemistry,drug effects,metabolism,physiology

Ligands Nuclear Proteins Receptors, Cytoplasmic and Nuclear Transcription Factors