Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece.

Journal of clinical microbiology ·Vol. 38 ·No. 3 ·2000-03-00 ·页码 1290-2

Tsakris A, Pournaras S, Woodford N, Palepou MF, Babini GS, Douboyas J, Livermore DM

Abstract

Resistance to imipenem and meropenem was observed in 211 (16.5%) isolates of Pseudomonas aeruginosa recovered in a Greek university hospital during 1996 to 1998. In six isolates selected from throughout this period, high-level resistance to both carbapenems (MICs >/= 128 microg/ml) was associated with production of the class B beta-lactamase VIM-1. bla(VIM)-bearing isolates belonged to serotype O:12 and were indistinguishable by pulsed-field gel electrophoresis.

MeSH 主题词

Anti-Bacterial Agents/pharmacology Bacterial Proteins Disease Outbreaks Drug Resistance, Microbial Greece/epidemiology Hospitals, University Humans Imipenem/pharmacology Inpatients Meropenem Microbial Sensitivity Tests Pseudomonas Infections/epidemiology,microbiology Pseudomonas aeruginosa/classification,drug effects,isolation & purification Serotyping Thienamycins/pharmacology beta-Lactamases/biosynthesis

化学物质

Anti-Bacterial Agents Bacterial Proteins Thienamycins Imipenem beta-Lactamases carbapenemase Meropenem

作者与单位

共 7 位作者，点击展开单位 / ORCID

Tsakris A

Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54 006 Thessaloniki, Greece. [email protected]

Pournaras S

Woodford N

Palepou M F

Babini G S

Douboyas J

Livermore D M

Article Info

Journal

Journal of clinical microbiology

Abbr.

J Clin Microbiol

ISSN

0095-1137

DOI

10.1128/JCM.38.3.1290-1292.2000

Corresponding email

[email protected]

Published

2000-03-00

页码

1290-2

Language

English

Country/Region

United States

NLM ID

7505564

External Links

PubMed source DOI: 10.1128/JCM.38.3.1290-1292.2000 View journal details

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Outbreak of infections caused by Pseudomonas aeruginosa producing VIM-1 carbapenemase in Greece.

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