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PMID: 10712947 Published · ppublish English Comparative Study Journal Article Review

Analysis of large-scale gene expression data.

Current opinion in immunology ·Vol. 12 ·No. 2 ·2000-04-00 ·Pages 201-5

Sherlock G

Abstract

The advent of cDNA and oligonucleotide microarray technologies has led to a paradigm shift in biological investigation, such that the bottleneck in research is shifting from data generation to data analysis. Hierarchical clustering, divisive clustering, self-organizing maps and k-means clustering have all been recently used to make sense of this mass of data.

MeSH Terms
Algorithms Animals Artifacts Cell Cycle/genetics Cluster Analysis Data Interpretation, Statistical Electronic Data Processing/methods Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Oligonucleotide Array Sequence Analysis
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Sherlock G
Department of Genetics, Stanford University Medical Center, Stanford, 94306-5120, USA. [email protected]
Article Info
Journal
Current opinion in immunology
Abbr.
Curr Opin Immunol
ISSN
0952-7915
DOI
10.1016/s0952-7915(99)00074-6
Email
[email protected]
Published
2000-04-00
Pages
201-5
Language
English
Region
England
NLM ID
8900118
Subset
IM
External Links
PubMed source DOI: 10.1016/s0952-7915(99)00074-6 View journal details
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